Short-term mortality rates during a decade of improved air quality in Erfurt, Germany.
Identifieur interne : 000398 ( Main/Exploration ); précédent : 000397; suivant : 000399Short-term mortality rates during a decade of improved air quality in Erfurt, Germany.
Auteurs : Susanne Breitner [Allemagne] ; Matthias Stölzel ; Josef Cyrys ; Mike Pitz ; Gabriele Wölke ; Wolfgang Kreyling ; Helmut Küchenhoff ; Joachim Heinrich ; H-Erich Wichmann ; Annette PetersSource :
- Environmental health perspectives [ 1552-9924 ] ; 2009.
Descripteurs français
- KwdFr :
- MESH :
- Wicri :
- geographic : Allemagne.
English descriptors
- KwdEn :
- MESH :
- chemical , analysis : Particulate Matter.
- geographic : Germany.
- Humans, Mortality, Particle Size, Regression Analysis, Risk Assessment, Sensitivity and Specificity.
Abstract
BACKGROUND
Numerous studies have shown associations between ambient air pollution and daily mortality.
OBJECTIVES
Our goal was to investigate the association of ambient air pollution and daily mortality in Erfurt, Germany, over a 10.5-year period after the German unification, when air quality improved.
METHODS
We obtained daily mortality counts and data on mass concentrations of particulate matter (PM)<10 microm in aerodynamic diameter (PM10), gaseous pollutants, and meteorology in Erfurt between October 1991 and March 2002. We obtained ultrafine particle number concentrations (UFP) and mass concentrations of PM<2.5 microm in aerodynamic diameter (PM2.5) from September 1995 to March 2002. We analyzed the data using semiparametric Poisson regression models adjusting for trend, seasonality, influenza epidemics, day of the week, and meteorology. We evaluated cumulative associations between air pollution and mortality using polynomial distributed lag (PDL) models and multiday moving averages of air pollutants. We evaluated changes in the associations over time in time-varying coefficient models.
RESULTS
Air pollution concentrations decreased over the study period. Cumulative exposure to UFP was associated with increased mortality. An interquartile range (IQR) increase in the 15-day cumulative mean UFP of 7,649 cm(-3) was associated with a relative risk (RR) of 1.060 [95% confidence interval (CI), 1.008-1.114] for PDL models and an RR/IQR of 1.055 (95% CI, 1.011-1.101) for moving averages. RRs decreased from the mid-1990s to the late 1990s.
CONCLUSION
Results indicate an elevated mortality risk from short-term exposure to UFP. They further suggest that RRs for short-term associations of air pollution decreased as pollution control measures were implemented in Eastern Germany.
DOI: 10.1289/ehp.11711
PubMed: 19337521
PubMed Central: PMC2661916
Affiliations:
Links toward previous steps (curation, corpus...)
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sort="Breitner, Susanne" uniqKey="Breitner S" first="Susanne" last="Breitner">Susanne Breitner</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany. susanne.breitner@helmholtz-muenchen.de</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Stolzel, Matthias" sort="Stolzel, Matthias" uniqKey="Stolzel M" first="Matthias" last="Stölzel">Matthias Stölzel</name></author><author><name sortKey="Cyrys, Josef" sort="Cyrys, Josef" uniqKey="Cyrys J" first="Josef" last="Cyrys">Josef Cyrys</name></author><author><name sortKey="Pitz, Mike" sort="Pitz, Mike" uniqKey="Pitz M" first="Mike" last="Pitz">Mike Pitz</name></author><author><name sortKey="Wolke, Gabriele" sort="Wolke, Gabriele" uniqKey="Wolke G" first="Gabriele" last="Wölke">Gabriele Wölke</name></author><author><name sortKey="Kreyling, Wolfgang" sort="Kreyling, Wolfgang" uniqKey="Kreyling W" first="Wolfgang" last="Kreyling">Wolfgang Kreyling</name></author><author><name sortKey="Kuchenhoff, Helmut" sort="Kuchenhoff, Helmut" uniqKey="Kuchenhoff H" first="Helmut" last="Küchenhoff">Helmut Küchenhoff</name></author><author><name sortKey="Heinrich, Joachim" sort="Heinrich, Joachim" uniqKey="Heinrich J" first="Joachim" last="Heinrich">Joachim Heinrich</name></author><author><name sortKey="Wichmann, H Erich" sort="Wichmann, H Erich" uniqKey="Wichmann H" first="H-Erich" last="Wichmann">H-Erich Wichmann</name></author><author><name sortKey="Peters, Annette" sort="Peters, Annette" uniqKey="Peters A" first="Annette" last="Peters">Annette Peters</name></author></analytic><series><title level="j">Environmental health perspectives</title><idno type="eISSN">1552-9924</idno><imprint><date when="2009" type="published">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Germany (MeSH)</term><term>Humans (MeSH)</term><term>Mortality (MeSH)</term><term>Particle Size (MeSH)</term><term>Particulate Matter (analysis)</term><term>Regression Analysis (MeSH)</term><term>Risk Assessment (MeSH)</term><term>Sensitivity and Specificity (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Allemagne (MeSH)</term><term>Analyse de régression (MeSH)</term><term>Appréciation des risques (MeSH)</term><term>Humains (MeSH)</term><term>Matière particulaire (analyse)</term><term>Mortalité (MeSH)</term><term>Sensibilité et spécificité (MeSH)</term><term>Taille de particule (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Particulate Matter</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Germany</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>Matière particulaire</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term><term>Mortality</term><term>Particle Size</term><term>Regression Analysis</term><term>Risk Assessment</term><term>Sensitivity and Specificity</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Allemagne</term><term>Analyse de régression</term><term>Appréciation des risques</term><term>Humains</term><term>Mortalité</term><term>Sensibilité et spécificité</term><term>Taille de particule</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Allemagne</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>Numerous studies have shown associations between ambient air pollution and daily mortality.</p></div><div type="abstract" xml:lang="en"><p><b>OBJECTIVES</b></p><p>Our goal was to investigate the association of ambient air pollution and daily mortality in Erfurt, Germany, over a 10.5-year period after the German unification, when air quality improved.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>We obtained daily mortality counts and data on mass concentrations of particulate matter (PM)<10 microm in aerodynamic diameter (PM10), gaseous pollutants, and meteorology in Erfurt between October 1991 and March 2002. We obtained ultrafine particle number concentrations (UFP) and mass concentrations of PM<2.5 microm in aerodynamic diameter (PM2.5) from September 1995 to March 2002. We analyzed the data using semiparametric Poisson regression models adjusting for trend, seasonality, influenza epidemics, day of the week, and meteorology. We evaluated cumulative associations between air pollution and mortality using polynomial distributed lag (PDL) models and multiday moving averages of air pollutants. We evaluated changes in the associations over time in time-varying coefficient models.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>Air pollution concentrations decreased over the study period. Cumulative exposure to UFP was associated with increased mortality. An interquartile range (IQR) increase in the 15-day cumulative mean UFP of 7,649 cm(-3) was associated with a relative risk (RR) of 1.060 [95% confidence interval (CI), 1.008-1.114] for PDL models and an RR/IQR of 1.055 (95% CI, 1.011-1.101) for moving averages. RRs decreased from the mid-1990s to the late 1990s.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>Results indicate an elevated mortality risk from short-term exposure to UFP. They further suggest that RRs for short-term associations of air pollution decreased as pollution control measures were implemented in Eastern Germany.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">19337521</PMID><DateCompleted><Year>2009</Year><Month>07</Month><Day>16</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>13</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1552-9924</ISSN><JournalIssue CitedMedium="Internet"><Volume>117</Volume><Issue>3</Issue><PubDate><Year>2009</Year><Month>Mar</Month></PubDate></JournalIssue><Title>Environmental health perspectives</Title><ISOAbbreviation>Environ. Health Perspect.</ISOAbbreviation></Journal><ArticleTitle>Short-term mortality rates during a decade of improved air quality in Erfurt, Germany.</ArticleTitle><Pagination><MedlinePgn>448-54</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1289/ehp.11711</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Numerous studies have shown associations between ambient air pollution and daily mortality.</AbstractText><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">Our goal was to investigate the association of ambient air pollution and daily mortality in Erfurt, Germany, over a 10.5-year period after the German unification, when air quality improved.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">We obtained daily mortality counts and data on mass concentrations of particulate matter (PM)<10 microm in aerodynamic diameter (PM10), gaseous pollutants, and meteorology in Erfurt between October 1991 and March 2002. We obtained ultrafine particle number concentrations (UFP) and mass concentrations of PM<2.5 microm in aerodynamic diameter (PM2.5) from September 1995 to March 2002. We analyzed the data using semiparametric Poisson regression models adjusting for trend, seasonality, influenza epidemics, day of the week, and meteorology. We evaluated cumulative associations between air pollution and mortality using polynomial distributed lag (PDL) models and multiday moving averages of air pollutants. We evaluated changes in the associations over time in time-varying coefficient models.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Air pollution concentrations decreased over the study period. Cumulative exposure to UFP was associated with increased mortality. An interquartile range (IQR) increase in the 15-day cumulative mean UFP of 7,649 cm(-3) was associated with a relative risk (RR) of 1.060 [95% confidence interval (CI), 1.008-1.114] for PDL models and an RR/IQR of 1.055 (95% CI, 1.011-1.101) for moving averages. RRs decreased from the mid-1990s to the late 1990s.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Results indicate an elevated mortality risk from short-term exposure to UFP. They further suggest that RRs for short-term associations of air pollution decreased as pollution control measures were implemented in Eastern Germany.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Breitner</LastName><ForeName>Susanne</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany. susanne.breitner@helmholtz-muenchen.de</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stölzel</LastName><ForeName>Matthias</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Cyrys</LastName><ForeName>Josef</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Pitz</LastName><ForeName>Mike</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Wölke</LastName><ForeName>Gabriele</ForeName><Initials>G</Initials></Author><Author ValidYN="Y"><LastName>Kreyling</LastName><ForeName>Wolfgang</ForeName><Initials>W</Initials></Author><Author ValidYN="Y"><LastName>Küchenhoff</LastName><ForeName>Helmut</ForeName><Initials>H</Initials></Author><Author ValidYN="Y"><LastName>Heinrich</LastName><ForeName>Joachim</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Wichmann</LastName><ForeName>H-Erich</ForeName><Initials>HE</Initials></Author><Author ValidYN="Y"><LastName>Peters</LastName><ForeName>Annette</ForeName><Initials>A</Initials></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>R01 ES014843</GrantID><Acronym>ES</Acronym><Agency>NIEHS NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType><PublicationType UI="D013486">Research Support, U.S. Gov't, Non-P.H.S.</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2008</Year><Month>10</Month><Day>07</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Environ Health Perspect</MedlineTA><NlmUniqueID>0330411</NlmUniqueID><ISSNLinking>0091-6765</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D052638">Particulate Matter</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D005858" MajorTopicYN="N" Type="Geographic">Germany</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009026" MajorTopicYN="Y">Mortality</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010316" MajorTopicYN="N">Particle Size</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D052638" MajorTopicYN="N">Particulate Matter</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="Y">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012044" MajorTopicYN="N">Regression Analysis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018570" MajorTopicYN="N">Risk Assessment</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012680" MajorTopicYN="N">Sensitivity and Specificity</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">accountability research</Keyword><Keyword MajorTopicYN="N">air pollution</Keyword><Keyword MajorTopicYN="N">improved air quality</Keyword><Keyword MajorTopicYN="N">mortality</Keyword><Keyword MajorTopicYN="N">particulate matter</Keyword><Keyword MajorTopicYN="N">ultrafine particles</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate 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Peters</name><name sortKey="Pitz, Mike" sort="Pitz, Mike" uniqKey="Pitz M" first="Mike" last="Pitz">Mike Pitz</name><name sortKey="Stolzel, Matthias" sort="Stolzel, Matthias" uniqKey="Stolzel M" first="Matthias" last="Stölzel">Matthias Stölzel</name><name sortKey="Wichmann, H Erich" sort="Wichmann, H Erich" uniqKey="Wichmann H" first="H-Erich" last="Wichmann">H-Erich Wichmann</name><name sortKey="Wolke, Gabriele" sort="Wolke, Gabriele" uniqKey="Wolke G" first="Gabriele" last="Wölke">Gabriele Wölke</name></noCountry><country name="Allemagne"><noRegion><name sortKey="Breitner, Susanne" sort="Breitner, Susanne" uniqKey="Breitner S" first="Susanne" last="Breitner">Susanne Breitner</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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